TESPA1 Antibody, Biotin conjugated

Cusabio

TESPA1 Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

TESPA1

thymocyte expressed, positive selection associated 1

HSPC257, ITPRID3, KIAA0748, protein TESPA1, thymocyte-expressed positive selection-associated protein 1

Rabbit

IgG

Protein TESPA1

Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development. Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.

Human

-20°C or -80°C

41116161