![Tetranactin [33956-61-5] Tetranactin [33956-61-5]](https://www.targetmol.com/group3/M00/36/E3/CgoaEWayRUGENU0BAAAAAKmX29E403.png)
Tetranactin [33956-61-5]
T37052
Overview
- SupplierTargetMol Chemicals
- Product NameTetranactin [33956-61-5]
- Delivery Days Customer44
- CAS Number33956-61-5
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameTetranactin
- Molecular FormulaC44H72O12
- Molecular Weight793.048
- Scientific DescriptionTetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S. aureus and has antibacterial, insecticidal, and mitogenic activities. It exhibits an equilibrium permeability ratio 1,000-fold greater for lithium than sodium or cesium ions accross bilayer membranes at low voltages. Tetranactin inhibits the growth of Gram-positive bacteria and C. miyabeanus and R. solani fungi when used at concentrations less than 0.9 microg/ml. Tetranactin (0.5-1.5 microg per insect) dose-dependently increases the mortality of adult C. chinensis weevils up to 100% and has mitogenic activity against T. telarius when sprayed onto plants with an LC50 value of 9.2 microg/ml. It reduces IL-1beta- and cAMP-induced secretion of phospholipase A2 (PLA2) from rat mesangial cells (IC50s = 43 and 33 nM, respectively). Tetranactin (50 ng/ml) suppresses the proliferation of human T lymphocytes induced by allogeneic cells and IL-2 and supresses the generation of cytotoxic T lymphocytes in mixed lymphocyte cultures.
- Shelf life instruction3 years
- SMILES[H][C@@]12CC[C@@]([H])(O1)[C@@H](C)C(=O)O[C@H](CC)C[C@@]1([H])CC[C@]([H])(O1)[C@H](C)C(=O)O[C@@H](CC)C[C@]1([H])CC[C@@]([H])(O1)[C@@H](C)C(=O)O[C@H](CC)C[C@@]1([H])CC[C@]([H])(O1)[C@H](C)C(=O)O[C@@H](CC)C2
- Storage Instruction-20°C
- UNSPSC12352200