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Tetranactin [33956-61-5]

Tetranactin [33956-61-5]

T37052
TargetMol Chemicals
CAS Number33956-61-5
Product group Chemicals
Molecular Weight793.048
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Tetranactin [33956-61-5]
  • Delivery Days Customer
    44
  • CAS Number
    33956-61-5
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Tetranactin
  • Molecular Formula
    C44H72O12
  • Molecular Weight
    793.048
  • Scientific Description
    Tetranactin is a macrotetrolide and a monovalent cation ionophore that has been found in S. aureus and has antibacterial, insecticidal, and mitogenic activities. It exhibits an equilibrium permeability ratio 1,000-fold greater for lithium than sodium or cesium ions accross bilayer membranes at low voltages. Tetranactin inhibits the growth of Gram-positive bacteria and C. miyabeanus and R. solani fungi when used at concentrations less than 0.9 microg/ml. Tetranactin (0.5-1.5 microg per insect) dose-dependently increases the mortality of adult C. chinensis weevils up to 100% and has mitogenic activity against T. telarius when sprayed onto plants with an LC50 value of 9.2 microg/ml. It reduces IL-1beta- and cAMP-induced secretion of phospholipase A2 (PLA2) from rat mesangial cells (IC50s = 43 and 33 nM, respectively). Tetranactin (50 ng/ml) suppresses the proliferation of human T lymphocytes induced by allogeneic cells and IL-2 and supresses the generation of cytotoxic T lymphocytes in mixed lymphocyte cultures.
  • Shelf life instruction
    3 years
  • SMILES
    [H][C@@]12CC[C@@]([H])(O1)[C@@H](C)C(=O)O[C@H](CC)C[C@@]1([H])CC[C@]([H])(O1)[C@H](C)C(=O)O[C@@H](CC)C[C@]1([H])CC[C@@]([H])(O1)[C@@H](C)C(=O)O[C@H](CC)C[C@@]1([H])CC[C@]([H])(O1)[C@H](C)C(=O)O[C@@H](CC)C2
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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