TFE3 Antibody

Cusabio

TFE3 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

TFE3

transcription factor binding to IGHM enhancer 3

MRXSPF, RCCP2, RCCX1, TFEA, bHLHe33, transcription factor E3, class E basic helix-loop-helix protein 33, transcription factor E family, member A, transcription factor for IgH enhancer, transcription factor for immunoglobulin heavy-chain enhancer 3

Rabbit

IgG

Transcription factor E3

Transcription factor that specifically recognizes and binds E-box sequences (5-CANNTG-3). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site.

Human

-20°C or -80°C

41116161