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TFF1 antibody

GTX28762
GeneTex
ApplicationsELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTFF1
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Overview

  • Supplier
    GeneTex
  • Product Name
    TFF1 antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    This antibody is specific to pS2 protein, also known as pNR-2.
  • Application Supplier Note
    Immunohistochemistry 1:25-1:50. This antibody can be used on both frozen and formalin-fixed, paraffin-embedded tissue sections. Prolonged fixation in buffered formalin can destroy the epitope. This antibody may be used at a dilution of 1:25-1:50. For paraffin sections, incubation of primary antibody for one hour at 37 is recommended. The optimum conditions should be determined by the individual laboratory.
  • Applications
    ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID7031
  • Target name
    TFF1
  • Target description
    trefoil factor 1
  • Target synonyms
    BCEI; breast cancer estrogen-inducible protein; breast cancer estrogen-inducible sequence; D21S21; gastrointestinal trefoil protein pS2; HP1.A; HPS2; pNR-2; polypeptide P1.A; protein pS2; pS2; trefoil factor 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP04155
  • Protein Name
    Trefoil factor 1
  • Scientific Description
    Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
  • Reactivity
    Human
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Trefoil factor 1 stimulates both pancreatic cancer and stellate cells and increases metastasis. Arumugam T et al., 2011 Aug, Pancreas
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