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TGF beta 3 antibody

GTX15537
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTGFB3
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Overview

  • Supplier
    GeneTex
  • Product Name
    TGF beta 3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: Use at a dilution of 1/100 for 10 minutes at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 minutes followed by cooling at RT for 20 minutes. GTX15537 demonstrates cytoplasmic staining. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 47 kDa. Optimal dilutions/concentrations should be determined by the end user.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID7043
  • Target name
    TGFB3
  • Target description
    transforming growth factor beta 3
  • Target synonyms
    ARVD; ARVD1; LDS5; prepro-transforming growth factor beta-3; RNHF; TGF-beta3; transforming growth factor beta-3 proprotein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP10600
  • Protein Name
    Transforming growth factor beta-3
  • Scientific Description
    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Aug 2016]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203