TGFbeta-IN-2 [2387678-02-4]
HY-146434
CAS Number2387678-02-4
Product group Chemicals
Estimated Purity99.37
Molecular Weight378.42
Overview
- SupplierMedChem Express
- Product NameTGFbeta-IN-2 [2387678-02-4]
- Delivery Days Customer5
- CAS Number2387678-02-4
- CertificationResearch Use Only
- Estimated Purity99.37
- Molecular FormulaC22H22N2O4
- Molecular Weight378.42
- Scientific DescriptionTGFbeta-IN-2 is an orally active TGF-beta inhibitor. TGFbeta-IN-2 suppresses the TGF-beta-induced protein expression of COL1A1, alpha-SMA, and p-Smad3 in vitro. TGFbeta-IN-2 demonstrates excellent anti-fibrotic efficacy in Bleomycin (HY-108345)-induced pulmonary fibrosis model. TGFbeta-IN-2 can be used for the study of pulmonary fibrosis[1].
- SMILESO=C(NC1=CC=C(C=C1)OC2=CC(OC3=CC=CC=C32)=O)CN4CCCCC4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200