TGFbetaRI-IN-5 [2541690-15-5]

MedChem Express

TGFbetaRI-IN-5 [2541690-15-5]

10

2541690-15-5

Research Use Only

C16H12N2O6

328.28

TGFbetaRI-IN-5 (Compound 4b) is a potent inhibitor of TGFbetaRI with an IC50 of 0.08 microM. TGFbetaRI-IN-5 displays amazing anticancer activity 5-7 times that of reference agent against all the tested cell lines. TGFbetaRI-IN-5 enhances apoptosis and arrested G2/M phase of cell cycle[1].

CC(N(C1=CC=CC=C1C(O)=O)C(C2=CC=C(C=C2)[N+]([O-])=O)=O)=O

12131703