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ProductsBack/TGN46 antibody

TGN46 antibody

GTX74290
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
DownloadDatasheet
Product group Antibodies
ReactivityHuman
TargetTGOLN2
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Overview

  • Supplier
    GeneTex
  • Product Name
    TGN46 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1/500-1/1,000. IHC-Fr: 1/50-1/100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID10618
  • Target name
    TGOLN2
  • Target description
    trans-golgi network protein 2
  • Target synonyms
    hTGN46; hTGN48; hTGN51; TGN38; TGN38 homolog; TGN46; TGN48; TGN51; trans-Golgi network glycoprotein 46; trans-Golgi network glycoprotein 48; trans-Golgi network glycoprotein 51; trans-Golgi network integral membrane protein 2; trans-Golgi network protein TGN51; TTGN2
  • Host
    Sheep
  • Isotype
    IgG
  • Protein IDO43493
  • Protein Name
    Trans-Golgi network integral membrane protein 2
  • Scientific Description
    This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2011]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Fatty Acid Uptake in Liver Hepatocytes Induces Relocalization and Sequestration of Intracellular Copper. Harder NHO et al., 2022, Front Mol Biosci
    Read more
  • Single nucleotide polymorphisms in the human ATP7B gene modify the properties of the ATP7B protein. McCann CJ et al., 2019 Jun 19, Metallomics
    Read more
  • SNX3-retromer requires an evolutionary conserved MON2:DOPEY2:ATP9A complex to mediate Wntless sorting and Wnt secretion. McGough IJ et al., 2018 Sep 13, Nat Commun
    Read more
  • Sorting nexin-21 is a scaffold for the endosomal recruitment of huntingtin. Danson CM et al., 2018 Sep 10, J Cell Sci
    Read more
  • Abnormal glycosylation in Joubert syndrome type 10. Kane MS et al., 2017, Cilia
    Read more
  • Neuronal differentiation is associated with a redox-regulated increase of copper flow to the secretory pathway. Hatori Y et al., 2016 Feb 16, Nat Commun
    Read more
  • Disruption of Golgi morphology and altered protein glycosylation in PLA2G6-associated neurodegeneration. Davids M et al., 2016 Mar, J Med Genet
    Read more
  • Genome-wide RNAi ionomics screen reveals new genes and regulation of human trace element metabolism. Malinouski M et al., 2014, Nat Commun
    Read more
  • Diverse functional properties of Wilson disease ATP7B variants. Huster D et al., 2012 Apr, Gastroenterology
    Read more
  • Difference in stability of the N-domain underlies distinct intracellular properties of the E1064A and H1069Q mutants of copper-transporting ATPase ATP7B. Dmitriev OY et al., 2011 May 6, J Biol Chem
    Read more