TGR5 Receptor Agonist 3 [2643391-08-4]
HY-146453
CAS Number2643391-08-4
Product group Chemicals
Molecular Weight513.54
Overview
- SupplierMedChem Express
- Product NameTGR5 Receptor Agonist 3 [2643391-08-4]
- Delivery Days Customer10
- CAS Number2643391-08-4
- CertificationResearch Use Only
- Molecular FormulaC29H27N3O6
- Molecular Weight513.54
- Scientific DescriptionTGR5 Receptor Agonist 3 (Compound 19) is a soft-agent G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonist with reduced gallbladder-filling effects (favorable gallbladder safety), with EC50s of 16.4 and 209 nM for hTGR5 and mTGR5, respectively.
- SMILESCCOCOC(C1=COC2=C1C=C(C=C2)OC3=C(C=NC=C3)C(N4CCN(C5=C4C=CC=C5)C6CC6)=O)=O
- UNSPSC12131703