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TGR5 Receptor Agonist (Standard) [1197300-24-5]

HY-14229R
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    TGR5 Receptor Agonist (Standard) [1197300-24-5]
  • Delivery Days Customer
    999
  • Certification
    Research Use Only
  • Scientific Description
    TGR5 Receptor Agonist (Standard) is the analytical standard of TGR5 Receptor Agonist. This product is intended for research and analytical applications. TGR5 Receptor Agonist (CCDC), a potent Takeda G protein-coupled receptor 5 (TGR5; GPCR19) agonist, shows improved potency in the U2-OS cells and melanophore cells with pEC50s of 6.8 and 7.5, respectively. TGR5 Receptor Agonist can induce peripheral and central hypersensitivity to bladder distension in mice, and increase intracellular Ca2+ concentration. TGR5 Receptor Agonist can also reduces food intake and improves insulin responsiveness, in diet-induced obese mice. TGR5 Receptor Agonist can be used to research diabetes, bladder hypersensitivity and anti-obesity[1][2][3][4].
  • UNSPSC
    41116100