TGS1 Antibody

Cusabio

TGS1 Antibody

20

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

TGS1

trimethylguanosine synthase 1

NCOA6IP, PIMT, PIPMT, trimethylguanosine synthase, CLL-associated antigen KW-2, PRIP-interacting protein with methyltransferase motif, cap-specific guanine-N(2) methyltransferase, cap-specific guanine-N2 methyltransferase, hepatocellular carcinoma-associated antigen 137, nuclear receptor coactivator 6-interacting protein

Rabbit

IgG

Trimethylguanosine synthase

Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine (m7G) caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine (m(2,2,7)G) cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies (CBs). Plays a role in transcriptional regulation.

Human, Mouse

-20°C or -80°C

41116161