TH1020

MedChem Express

TH1020 [1841460-82-9]

9

1841460-82-9

Research Use Only

99.81

C23H15N7S2

453.54

TH1020 is a potent and selective toll-like receptor 5 (TLR5)/flagellin complex antagonist with an IC50 of 0.85 microM. TH1020 inhbits flagellin-induced TLR5 signaling. TH1020 is inactive against TLR2, TLR3, TLR4, TLR7 and TLR8[1].

C12=NC=NC(SC3=NN=C(N3CC4=CC=CC=C4)C5=CC=NC=C5)=C1SC6=NC=CC=C62

-20°C,2°C to 8°C

12352200