TH1338 [1258494-60-8]

MedChem Express

TH1338 [1258494-60-8]

10

1258494-60-8

Research Use Only

98.77

C22H21N3O4

391.42

TH1338 (compound 3b), an orally active camptothecin derivative and a potent chemotherapeutic agent for cancer, demonstrates excellent cytotoxic potency against human tumor cell lines in vitro. TH1338 (compound 3b) possesses significant brain penetration, favorable efflux pump properties, and hematological toxicity profile[1][2].

O=C1[C@](O)(CC)C2=C(CO1)C(N3CC4=C(CC)C5=CC=CC=C5N=C4C3=C2N)=O

-20°C,2°C to 8°C

12352200