Thailanstatin A cyclohexane diamine (formic)

MedChem Express

Thailanstatin A cyclohexane diamine (formic)

5

Research Use Only

93.74

C35H55N3O10

677.83

Thailanstatin A cyclohexane diamine formic is an analog of Spliceostatin (HY-16466). Thailanstatin A cyclohexane diamine formic inhibits proliferations of cells N87 (IC50 is 0.33 microM), BT474 (IC50 is 0.34 microM), MDA-MB-361-DYT2 (IC50 is 0.88 microM) and MDA-MB-468 (IC50 is 0.27 microM). Thailanstatin A cyclohexane diamine formic is used as a drug-linker conjugate for ADC molecule[1].

O[C@H]1[C@@]2(C[C@H](O[C@@H]1/C=C/C(C)=C/C[C@H]3[C@H](C[C@H]([C@H](O3)C)NC(/C=C\[C@H](C)OC(C)=O)=O)C)CC(N[C@H]4CC[C@@H](CC4)N)=O)CO2.O=CO

-20°C

41115800