THAL-SNS-032

AbMole BioScience

THAL-SNS-032

9

2139287-33-3

Chemical

Research Use Only

869.02

THAL-SNS-032 is a selective CDK9 degrader PROTAC consisting of a CDK-binding SNS-032 ligand linked to a thalidomide derivative that binds the E3 ubiquitin ligase Cereblon (CRBN).

CC(C)(C)C1=CN=C(CSC2=CN=C(NC(=O)C3CCN(CC3)CC(=O)NCCOCCOCCOCCNC4=CC=CC5=C4C(=O)N(C6CCC(=O)NC6=O)C5=O)S2)O1

-20°C, sealed

12352200