Thalidomide 4-ether-PEG2-azide
HY-157515
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameThalidomide 4-ether-PEG2-azide
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC19H21N5O7
- Molecular Weight431.40
- Scientific DescriptionThalidomide 4-ether-PEG2-azide is a click chemistry modified cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide 4-ether-PEG2-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkynyl groups. Thalidomide 4-ether-PEG2-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs[1].
- SMILES[N-]=[N+]=NCCOCCOCCOC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
- UNSPSC41115800