Thalidomide-4-NH-PEG1-COO(t-Bu)
HY-W584522
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameThalidomide-4-NH-PEG1-COO(t-Bu)
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC22H27N3O7
- Molecular Weight445.47
- Scientific DescriptionThalidomide-4-NH-PEG1-COO(t-Bu) is a t-Bu modified Thalidomide (HY-14658), which acts as a Cereblon ligand to recruit CRBN protein. The t-Bu protecting group at the end of Thalidomide-4-NH-PEG1-COO(t-Bu) can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-COO(t-Bu) is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
- SMILESO=C(OC(C)(C)C)CCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
- UNSPSC41115800