Thalidomide-4-NH-PEG1-NH-Boc
HY-W584520
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameThalidomide-4-NH-PEG1-NH-Boc
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC22H28N4O7
- Molecular Weight460.48
- Scientific DescriptionThalidomide-4-NH-PEG1-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-4-NH-PEG1-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-4-NH-PEG1-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
- SMILESO=C(OC(C)(C)C)NCCOCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
- UNSPSC41115800