Thalidomide-5-O-CH2-COOH

MedChem Express

Thalidomide-5-O-CH2-COOH

5

Research Use Only

97.0

C15H12N2O7

332.26

Thalidomide-5-O-CH2-COOH is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-5-O-CH2-COOH acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-5-O-CH2-COOH is a key intermediate in the synthesis of PROTAC molecules designed based on CRBN.

O=C(O)COC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2=O)=O)C=C1

-20°C,2°C to 8°C

41115800