Thalidomide

MedChem Express

Thalidomide [50-35-1]

10

50-35-1

Research Use Only

99.92

C13H10N2O4

258.233

Thalidomide inhibits cereblon (CRBN), a part of the cullin-4 E3 ubiquitin ligase complex CUL4-RBX1-DDB1, with a K d of ~250 nM, and has immunomodulatory, anti-inflammatory and anti-angiogenic cancer properties. Thalidomide can work as molecular glue to potentiate substrate.

O=C1N(C2CCC(NC2=O)=O)C(C3=CC=CC=C31)=O

-20°C,2°C to 8°C

12352200