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Thalidomide-N-methylpiperazine

HY-169074
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Thalidomide-N-methylpiperazine
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C18H20N4O4
  • Molecular Weight
    356.38
  • Scientific Description
    Thalidomide-N-methylpiperazine is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-N-methylpiperazine can be used to synthesize PROTAC MLKL Degrader-2 (HY-169072) [1] to exhibit antinecroptotic activity on human cell lines and effectively degrade MLKL in the HT-29 xenograft mouse model[1].
  • SMILES
    CN1CCN(C2=CC3=C(C=C2)C(N(C3=O)C4CCC(NC4=O)=O)=O)CC1
  • UNSPSC
    41115800

MSDS

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