Thalidomide-NH-(CH2)2-NH-Boc [1957235-57-2]
HY-W584513
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameThalidomide-NH-(CH2)2-NH-Boc [1957235-57-2]
- Delivery Days Customer14
- CAS Number1957235-57-2
- CertificationResearch Use Only
- Molecular FormulaC20H24N4O6
- Molecular Weight416.43
- Scientific DescriptionThalidomide-NH-(CH2)2-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)2-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)2-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules.
- SMILESO=C(OC(C)(C)C)NCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
- UNSPSC41115800