Thalidomide-NH-(CH2)2-NH2 (TFA) [1957235-67-4]

MedChem Express

Thalidomide-NH-(CH2)2-NH2 (TFA) [1957235-67-4]

14

1957235-67-4

Research Use Only

C17H17F3N4O6

430.34

Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN proteins. Thalidomide-NH-(CH2)2-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules designed to synthesize small PROTAC molecules targeting SHP2 protein.

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCN)=O.O=C(O)C(F)(F)F

41115800