Thalidomide-O-amido-C4-N3 [2098488-36-7]

MedChem Express

Thalidomide-O-amido-C4-N3 [2098488-36-7]

10

2098488-36-7

Research Use Only

98.36

C19H20N6O6

428.40

Thalidomide-O-amido-C4-N3 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology. Thalidomide-O-amido-C4-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(N(C(CCC1=O)C(N1)=O)C2=O)C(C2=CC=C3)=C3OCC(NCCCCN=[N+]=[N-])=O

2°C to 8°C

41115800