Thalidomide-O-C5-azide
HY-157511
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameThalidomide-O-C5-azide
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC18H19N5O5
- Molecular Weight385.37
- Scientific DescriptionThalidomide-O-C5-azide is a click chemistry modification of the cereblon (CRBN) inhibitor Thalidomide (HY-14658). Thalidomide-O-C5-azide contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing alkyne groups. Thalidomide-O-C5-azide can be used as a ligand of E3 ubiquitin ligase and Linker conjugates (E3 Ligase Ligand-Linker Conjugates) for the synthesis of PROTACs[1].
- SMILES[N-]=[N+]=NCCCCCOC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O
- UNSPSC41115800