Thalidomide-O-PEG1-OH

MedChem Express

Thalidomide-O-PEG1-OH

5

Research Use Only

C15H14N2O6

318.28

Thalidomide-O-PEG1-OH is a PROTAC linker featuring thalidomide with an O-ethyl alcohol. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction. Meanwhile, the hydroxyl is a versatile handle for forming more complex structures through a number of reactions.

O=C1NC(C(CC1)N2C(C3=C(C2=O)C(OCCO)=CC=C3)=O)=O

41115800