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Thalidomide-O-PEG2-propargyl [2098487-52-4]

HY-126458
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Thalidomide-O-PEG2-propargyl [2098487-52-4]
  • Delivery Days Customer
    10
  • CAS Number
    2098487-52-4
  • Certification
    Research Use Only
  • Estimated Purity
    98.26
  • Molecular Formula
    C20H20N2O7
  • Molecular Weight
    400.38
  • Scientific Description
    Thalidomide-O-PEG2-propargyl (E3 ligase Ligand-Linker Conjugates 32) is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. Thalidomide-O-PEG2-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • SMILES
    O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCOCCOCC#C)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    41115800