Thalidomide-PEG4-Propargyl [2098799-77-8]

MedChem Express

Thalidomide-PEG4-Propargyl [2098799-77-8]

10

2098799-77-8

Research Use Only

98.0

C24H28N2O9

488.49

Thalidomide-PEG4-Propargyl is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. Thalidomide-PEG4-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3OCCOCCOCCOCCOCC#C)=O

-20°C

41115800