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Theaflavin 3,3-digallate [30462-35-2]

Research Use Only
HY-N1992
MedChem Express
CAS Number30462-35-2
Product group Chemicals
Estimated Purity99.73
Molecular Weight868.70
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Theaflavin 3,3-digallate [30462-35-2]
  • Delivery Days Customer
    10
  • CAS Number
    30462-35-2
  • Certification
    Research Use Only
  • Estimated Purity
    99.73
  • Molecular Formula
    C43H32O20
  • Molecular Weight
    868.70
  • Scientific Description
    Theaflavin 3,3-digallate (TF-3) is a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 microM. Theaflavin 3,3-digallat directly binds to ZIKVpro (Kd=8.86 microM) and inhibits ZIKV replication. Theaflavin 3,3-digallat inhibits the activity of gp41 and NS2B-3 protease and has antiviral activity against HSV and HIV-1[1]. Theaflavin 3,3-digallate, the typical pigment in black tea, is a potent antitumor agent[2].
  • SMILES
    O=C(C1=CC(O)=C(C(O)=C1)O)O[C@H]2[C@H](OC3=CC(O)=CC(O)=C3C2)C4=C5C(C(C(O)=CC([C@@H]6[C@@H](CC7=C(O)C=C(O)C=C7O6)OC(C8=CC(O)=C(C(O)=C8)O)=O)=C5)=O)=C(C(O)=C4)O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200