Thi-DPPY [2307699-34-7]
HY-147742
CAS Number2307699-34-7
Product group Chemicals
Molecular Weight566.07
Overview
- SupplierMedChem Express
- Product NameThi-DPPY [2307699-34-7]
- Delivery Days Customer10
- CAS Number2307699-34-7
- CertificationResearch Use Only
- Molecular FormulaC28H28ClN5O4S
- Molecular Weight566.07
- Scientific DescriptionThi-DPPY (compound 8e) is a potent and orally active JAK3 inhibitor with IC50 values of 62.4, 1.38 nM for BTK, JAK, respectively. Thi-DPPY shows anti-proliferative activity against HBE cells. Thi-DPPY shows anti-inflammatory activity in vivo. Thi-DPPY has the potential for the research of idiopathic pulmonary fibrosis (IPF)[1].
- SMILESC=CC(NC1=CC(OC2=NC(NC3=CC(Cl)=C(C=C3)OCCCN4CCOCC4)=NC5=C2SC=C5)=CC=C1)=O
- UNSPSC12131703