Thiazole orange dimer YOYO 1 [143413-85-8]

TargetMol Chemicals

Thiazole orange dimer YOYO 1 [143413-85-8]

16

C49H58I4N6O2

1270.64

Thiazole orange dimer YOYO-1 is a green fluorescent dye used for DNA staining. It is a tetracationic homodimer of oxazole yellow (YO) and is typically provided as a tetraiodide salt. In aqueous buffer, the free YOYO-1 dye (lambdamax 458 nm; lambdamax 564 nm) exhibits low fluorescence quantum yield, but upon binding to double-stranded DNA through diintercalation, its fluorescence intensity increases by 3200 times (lambdamax 489 nm; lambdamax 509 nm).

CN(C1=CC=CC=C1O/2)C2=C/C3=CC=[N+](C4=C3C=CC=C4)CCC[N+](C)(C)CCC[N+](C)(C)CCC[N+]5=CC=C(C6=C5C=CC=C6)/C=C7N(C8=CC=CC=C8O\7)C.[I-].[I-].[I-].[I-]

-20°C

12352200