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Thielavin A

ORB1984932
Biorbyt
CAS Number71950-66-8
Product group Chemicals
Estimated Purity98.00%
Molecular Weight538.549
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Overview

  • Supplier
    Biorbyt
  • Product Name
    Thielavin A [71950-66-8]
  • Delivery Days Customer
    10
  • CAS Number
    71950-66-8
  • Certification
    Research Use Only
  • Estimated Purity
    98.00%
  • Molecular Formula
    C29H30O10
  • Molecular Weight
    538.549
  • Scientific Description
    Thielavin A is a fungal metabolite originally isolated from T. terricola that is related to thielavin B . Thielavin A inhibits COX, blocking both the conversion of arachidonic acid to prostaglandin H2 and the conversion of PGH2 to PGE2 . Thielavin A also inhibits glucose-6-phosphatase in rat liver microsomes (IC50 = 4.6 microM). It is a non-competitive inhibitor of alpha-glucosidase from S. cerevisiae (IC50 = 23.8 microM; Ki = 27.8 microM).
  • SMILES
    Cc1cc(O)c(C)c(O)c1C(=O)Oc1c(C)c(C)c(C(=O)Oc2c(C)c(C)c(C(O)=O)c(O)c2C)c(O)c1C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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