Thiocolchicine [2730-71-4]
HY-116852
CAS Number2730-71-4
Product group Chemicals
Estimated Purity99.77
Molecular Weight415.50
Overview
- SupplierMedChem Express
- Product NameThiocolchicine [2730-71-4]
- Delivery Days Customer10
- CAS Number2730-71-4
- CertificationResearch Use Only
- Estimated Purity99.77
- Molecular FormulaC22H25NO5S
- Molecular Weight415.50
- Scientific DescriptionThiocolchicine, a derivative modified in the C Ring of Colchicine (HY-16569) with enhanced biological properties. Thiocolchicine is a potent inhibitor of tubulin polymerization (IC50=2.5 microM) and competitively binds to tubulin with a Ki of 0.7 microM. Thiocolchicine induces cell apoptosis[1][2]. Thiocolchicine can be used as an ADC cytotoxin in ADC technology.
- SMILESCC(N[C@H](C1=C2)CCC3=CC(OC)=C(OC)C(OC)=C3C1=CC=C(SC)C2=O)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
MSDS
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