Thiophene-2 [420089-51-6]

MedChem Express

Thiophene-2 [420089-51-6]

10

420089-51-6

Research Use Only

99.90

C18H14F5NO3S

419.37

Thiophene-2 (TP2) is a specific polyketide synthase 13 (Pks13) inhibitor. Thiophene-2 inhibits mycolic acid biosynthesis and rapidly leads to mycobacterial cell death. Thiophene-2 is active against Mycobacterium tuberculosis with a MIC value of 1 microM, and has potent anti-tuberculosis activity[1].

O=C(OC)C1=C(SC2=C1CCCCC2)NC(C3=C(C(F)=C(C(F)=C3F)F)F)=O

-20°C,2°C to 8°C

12352200