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ProductsBack/THOC3 Antibody

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA822232LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA822232LA01HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA822232LA01HU at dilution of 1:100

THOC3 Antibody

CSB-PA822232LA01HU

ApplicationsELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman

TargetTHOC3

Overview

Supplier
Cusabio
Product Name
THOC3 Antibody
Delivery Days Customer
20
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID84321
Target name
THOC3
Target description
THO complex subunit 3
Target synonyms
THO3, hTREX45, THO complex subunit 3, TEX1 homolog, THO complex 3
Host
Rabbit
Isotype
IgG
Protein IDQ96J01
Protein Name
THO complex subunit 3
Scientific Description
Required for efficient export of polyadenylated RNA and spliced mRNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5 end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposis sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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