Western Blot Positive WB detected in: K562 whole cell lysate, SH-SY5Y whole cell lysate All lanes: THOC6 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 38, 35, 33 kDa Observed band size: 35 kDa
Western Blot Positive WB detected in: K562 whole cell lysate, SH-SY5Y whole cell lysate All lanes: THOC6 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 38, 35, 33 kDa Observed band size: 35 kDa
THOC6 Antibody
CSB-PA769793LA01HU
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetTHOC6
Overview
- SupplierCusabio
- Product NameTHOC6 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID79228
- Target nameTHOC6
- Target descriptionTHO complex subunit 6
- Target synonymsMMRFCGU, WDR58, fSAP35, THO complex subunit 6, THO complex 6, THO complex subunit 6 homolog, WD repeat domain 58, WD repeat-containing protein 58, functional spliceosome-associated protein 35
- HostRabbit
- IsotypeIgG
- Protein IDQ86W42
- Protein NameTHO complex subunit 6
- Scientific DescriptionActs as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5 end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposis sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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