THPN [100079-26-3]

MedChem Express

THPN [100079-26-3]

10

100079-26-3

Research Use Only

98.00

C15H22O4

266.33

THPN is a potent Nur77 agonist. THPN specifically binds the LBD of Nur77 (TR3) but not that of retinoic acid receptor alpha and PPARgamma with a Kd of 270 nM. THPN leads to Nur77 translocation to the mitochondria to induce autophagic cell death in melanoma[1][2].

CCCCCCCCC(C1=CC(O)=C(O)C(O)=C1)=O

-20°C,2°C to 8°C

12352200