
IHC-P analysis of mouse thyroid tissue using GTX25621 Thyroid Hormone Receptor alpha antibody. Right : Primary antibody Left : Negative control without primary antibody Antigen retrieval : 10mM sodium citrate (pH 6.0), microwaved for 8-15 min Dilution : 1:20
Thyroid Hormone Receptor alpha antibody
GTX25621
ApplicationsGel Shift Assay, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityAvian, Chicken, Human, Mouse, Primate, Rat, Sheep, Xenopus
TargetTHRA
Overview
- SupplierGeneTex
- Product NameThyroid Hormone Receptor alpha antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:200. ICC/IF: 1:10-1:200. IHC-P: 1:20-1:100. Gel supershift assays: 1:10. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsGel Shift Assay, ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7067
- Target nameTHRA
- Target descriptionthyroid hormone receptor alpha
- Target synonymsAR7, CHNG6, EAR7, ERB-T-1, ERBA, ERBA1, NR1A1, THRA1, THRA2, THRalpha, THRalpha1, THRalpha2, TRalpha, TRalpha1, TRalpha2, c-ERBA-1, c-erbA, thyroid hormone receptor alpha, EAR-7, ERBA-related 7, V-erbA-related protein 7, c-erbA protooncogene, c-erbA-alpha, nuclear receptor subfamily 1 group A member 1, thyroid hormone receptor alpha 1, thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), triiodothyronine receptor
- HostRabbit
- IsotypeIgG
- Protein IDP10827
- Protein NameThyroid hormone receptor alpha
- Scientific DescriptionThe protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- ReactivityAvian, Chicken, Human, Mouse, Primate, Rat, Sheep, Xenopus
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC41116161
References
- Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the Xenopus metamorphosing intestine. Hasebe T et al., 2020 Jun 1, Gen Comp EndocrinolRead this paper
- Sex Differences in Brain Thyroid Hormone Levels during Early Post-Hatching Development in Zebra Finch (Taeniopygia guttata). Yamaguchi S et al., 2017, PLoS OneRead this paper
- Thyroid hormone suppresses expression of stathmin and associated tumor growth in hepatocellular carcinoma. Tseng YH et al., 2016 Dec 9, Sci RepRead this paper


















![Western blot of rat hippocampal lysate showing specific immunolabeling of the ~50k TR-α1 and the ~58k TR-α2 protein using THRA antibody [2103] (GTX30162)](https://www.genetex.com/upload/website/prouct_img/normal/GTX30162/Thyroid-Hormone-Receptor-alpha-antibody-2103_Western-blot_GTX30162-1_w_23060722_587.webp)