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Thyroid hormone receptor antagonist (1-850) [251310-57-3]

HY-127024
MedChem Express
Product group Proteins / Signaling Molecules
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Thyroid hormone receptor antagonist (1-850) [251310-57-3]
  • Delivery Days Customer
    5
  • CAS Number
    251310-57-3
  • Certification
    Research Use Only
  • Estimated Purity
    99.04
  • Scientific Description
    Thyroid hormone receptor antagonist (1-850) is a competitive, selective and high-affinity thyroid hormone receptor (TR) antagonist with an IC50 of 1.5 microM for antagonizing the effect of T3 on TR. Thyroid hormone receptor antagonist (1-850) blocks T3-mediated interaction of TRalpha and TRbeta with nuclear receptor coactivator. Thyroid hormone receptor antagonist (1-850) has no effect on the activity of RARalpha[1][2][3].
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    41116124