Thyroid hormone receptor antagonist (1-850) [251310-57-3]

MedChem Express

Thyroid hormone receptor antagonist (1-850) [251310-57-3]

5

251310-57-3

Research Use Only

99.04

Thyroid hormone receptor antagonist (1-850) is a competitive, selective and high-affinity thyroid hormone receptor (TR) antagonist with an IC50 of 1.5 microM for antagonizing the effect of T3 on TR. Thyroid hormone receptor antagonist (1-850) blocks T3-mediated interaction of TRalpha and TRbeta with nuclear receptor coactivator. Thyroid hormone receptor antagonist (1-850) has no effect on the activity of RARalpha[1][2][3].

-20°C,2°C to 8°C

41116124