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ProductsBack/Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker)(TSHb/1317), CF405S conjugate, 0.1mg/mL [26628-22-8]
Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker)(TSHb/1317), CF405S conjugate, 0.1mg/mL [26628-22-8]

Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker)(TSHb/1317), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC041317
Biotium
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse
TargetTSHB
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Overview

  • Supplier
    Biotium
  • Product Name
    Thyroid Stimulating Hormone, beta (TSH beta) (Pituitary Marker)(TSHb/1317), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    TSHb/1317
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID7252
  • Target name
    TSHB
  • Target description
    thyroid stimulating hormone subunit beta
  • Target synonyms
    thyroid stimulating hormone beta; thyrotropin beta chain; thyrotropin subunit beta; TSH-B; TSH-BETA
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP01222
  • Protein Name
    Thyrotropin subunit beta
  • Scientific Description
    The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH) follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated non-covalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. TSH is synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulates the endocrine function of the thyroid gland. TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and triiodothyronine (T3). TSH production is controlled by a Thyrotropin-Releasing Hormone (TRH), which is manufactured in the hypothalamus and transported to the pituitary gland, where it increases TSH production and release. Somatostatin is also produced by the hypothalamus and has an opposite effect on the pituitary production of TSH, decreasing or inhibiting its release. TSH is a useful marker in classification of pituitary tumors and the study of pituitary disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203