Tiagabine (hydrochloride) [145821-59-6]
HY-B0696A
CAS Number145821-59-6
Product group Chemicals
Estimated Purity99.44
Molecular Weight412.01
Overview
- SupplierMedChem Express
- Product NameTiagabine (hydrochloride) [145821-59-6]
- Delivery Days Customer10
- CAS Number145821-59-6
- CertificationResearch Use Only
- Estimated Purity99.44
- Hazard Informationh302, h315, h319, h335
- Molecular FormulaC20H26ClNO2S2
- Molecular Weight412.01
- Scientific DescriptionTiagabine hydrochloride is an anticonvulsant agent and a selective inhibitor of the GAT-1 GABA transporter with a Ki of ~0.1 microM. Tiagabine hydrochloride potently and selectively inhibits GABA reuptake with IC50s of 67, 446 and 182 nM for [3H]GABA uptake in synaptosomes, neurons and glia, respectively. Tiagabine hydrochloride has neuroprotective properties[1][2][3][4][5][6][7][8].
- SMILESO=C([C@H]1CN(CC/C=C(C2=C(C)C=CS2)/C3=C(C)C=CS3)CCC1)O.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
![Tiagabine hydrochloride [145821-59-6] [145821-59-6]](https://www.targetmol.com/group3/M00/02/40/CgoaEWY7J8OEZCSzAAAAAJXFeOw838.png)