Tiazofurin

MedChem Express

Tiazofurin [60084-10-8]

5

60084-10-8

99.84

C9H12N2O5S

260.27

Tiazofurin (NSC 286193) is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotide (TAD), a potent inhibitor of IMP dehydrogenase (IMPDH) [1] . Tiazofurin also has anti- orthopoxvirus and anti-variola activities [2] .

O=C(N)C1=CSC([C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)=N1

2°C to 8°C

12352200