TIE1 antibody [12D9]

GeneTex

TIE1 antibody [12D9]

9

This antibody recognizes human Tie1 in western blot without cross reactivity with human Tie2.

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

12D9

200 ug/ml

Unconjugated

TIE1

tyrosine kinase with immunoglobulin like and EGF like domains 1

JTK14; LMPHM11; TIE; tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1; tyrosine-protein kinase receptor Tie-1

Mouse

IgG1

Tyrosine-protein kinase receptor Tie-1

This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]

Human

-20°C or -80°C,2°C to 8°C

12352203