Tigloylgomisin H

MedChem Express

Tigloylgomisin H [66069-55-4]

10

66069-55-4

Research Use Only

C28H36O8

500.58

Tigloylgomisin H is a lignan isolated from the fruits of S. chinensis , can induce quinone reductase (QR) activity in Hepa1c1c7 mouse hepatocarcinoma cells. Tigloylgomisin H functions as a monofunctional inducer that specifically upregulates phase II detoxification enzyme NQO1 through the NF-E2-related factor 2 (Nrf2)-ARE pathway, thus represents a potential liver cancer prevention agent [1] .

COC(C(OC)=C1)=C(OC(/C(C)=C/C)=O)C2=C1CC(C)C(C)(O)CC3=C2C(OC)=C(OC)C(OC)=C3

12352200