TIK-301 [118702-11-7]

MedChem Express

TIK-301 [118702-11-7]

10

118702-11-7

Research Use Only

C14H17ClN2O2

280.75

TIK-301 (PD-6735) is a chlorinated melatonin derivative and a potent, high-affinity and orally active melatonin MT1 and MT2 receptors agonist with Kis of 0.081 nM and 0.042 nM, respectively. TIK-301 is also a 5-HT2B/5-HT2C receptors antagonist with antidepressant action. TIK-301 has the potential for sleep disorders and other circadian rhythm disorders treatment[1][2][3].

CC(NC[C@@H](C1=CNC2=C1C=C(OC)C(Cl)=C2)C)=O

12352200