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Tilorone (dihydrochloride)

HY-B1080
MedChem Express
CAS Number27591-69-1
Product group Chemicals
Estimated Purity99.94
Molecular Weight483.47
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tilorone (dihydrochloride) [27591-69-1]
  • Delivery Days Customer
    10
  • CAS Number
    27591-69-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.94
  • Molecular Formula
    C25H36Cl2N2O3
  • Molecular Weight
    483.47
  • Scientific Description
    Tilorone dihydrochloride is an orally active interferon (IFN) inducer with broad-spectrum antiviral activities. Tilorone dihydrochloride possesses robust anti-Severe fever with thrombocytopenia syndrome virus (SFTSV) activity in vitro and in vivo through stimulation of host innate immunity. Tilorone dihydrochloride can penetrate the blood-brain barrier to activate HIF in the CNS [1] [2] [3] .Tilorone dihydrochloride exhibits an inhibitory activity with EC 50 of 230 nM against Ebola virus (EBOV) [4] .
  • SMILES
    O=C1C2=C(C3=C1C=C(OCCN(CC)CC)C=C3)C=CC(OCCN(CC)CC)=C2.[H]Cl.[H]Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200