TIM-3/HAVCR2, Human (HEK293, His)

MedChem Express

TIM-3/HAVCR2, Human (HEK293, His)

10

Research Use Only

98.0

HAVCR2

hepatitis A virus cellular receptor 2

CD366, HAVcr-2, KIM-3, SPTCL, TIM3, TIMD-3, TIMD3, Tim-3, hepatitis A virus cellular receptor 2, T cell immunoglobulin mucin 3, T-cell immunoglobulin and mucin domain 3, T-cell immunoglobulin and mucin domain-containing protein 3, T-cell immunoglobulin mucin family member 3, T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, kidney injury molecule-3

T cell immunoglobulin mucin-3 is an inhibitory receptor, and inhibits T cell functions. TIM-3 regulates immune responses in autoimmunity and cancer. TIM-3 has multiple different ligands: galectin 9, phosphatidylserine (PtdSer), CEACAM1 and HMGB1. The TIM-3-ligand axis is critical in the pathogenesis of numerous conditions, including autoimmune diseases, infections, cancers, transplant rejection, and chronic inflammation[1][2][3][4][5]. TIM-3/HAVCR2 Protein, Human (HEK293, His) is the recombinant human-derived TIM-3/HAVCR2 protein, expressed by HEK293 , with C-6*His labeled tag.

-20°C

41116100