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Timosaponin AIII [41059-79-4]

Timosaponin AIII [41059-79-4]

T3395
TargetMol Chemicals
CAS Number41059-79-4
Product group Chemicals
Estimated Purity99.61%
Molecular Weight740.92
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Timosaponin AIII [41059-79-4]
  • Delivery Days Customer
    4
  • CAS Number
    41059-79-4
  • Certification
    Research Use Only
  • Chemical Name
    Timosaponin AIII
  • Estimated Purity
    99.61%
  • Molecular Formula
    C39H64O13
  • Molecular Weight
    740.92
  • Scientific Description
    Timosaponin AIII (Timosaponin A3) induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 microM). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC50: 2.5 microM, BT474 cells; 6 microM, MDAMB231). The Timosaponin AIII pro-apoptotic response is selective for tumor cells over normal cells but autophagy is induced in both.
  • Shelf life instruction
    3 years
  • SMILES
    CC1C2C(CC3C4CCC5CC(CCC5(C)C4CCC23C)OC2OC(CO)C(O)C(O)C2OC2OC(CO)C(O)C(O)C2O)OC11CCC(C)CO1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200