TIP47 antibody

GeneTex

TIP47 antibody

9

This antibody is predicted to recognize TIP47 isoforms 1-4 (UniProt #O60664).

WB: 0.5 - 1 microg/mL. IHC-P: 10 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

PLIN3

perilipin 3

47 kDa MPR-binding protein; cargo selection protein TIP47; M6PRBP1; mannose-6-phosphate receptor-binding protein 1; perilipin-3; placental protein 17; PP17; tail-interacting protein, 47 kD; testicular tissue protein Li 114; TIP47

Rabbit

IgG

Perilipin-3

Tail-interacting protein (TIP47) is a cytosolic protein essential for the transport of mannose-6-phosphate receptors (MPRs) from endosomes to the trans-Golgi compartments in cells. TIP47 is recruited from the cytoplasm to the late endosomal surface by the Ras-associated protein Rab9 GTPase, enabling it to bind more efficiently to MPR cytoplasmic domains. Recently, it was shown that TIP47 regulates the expression of Rab9, as expression of siRNA to TIP47 in transfected cells dramatically decreased the half-life of the Rab9 protein in addition to stabilizing the subcellular localization of Rab9. At least two isoforms of TIP47 are known to exist.

Human, Rat

-20°C or -80°C,2°C to 8°C

12352203