Tipepidine (hydrochloride) [1449686-84-3]

MedChem Express

Tipepidine (hydrochloride) [1449686-84-3]

10

1449686-84-3

Research Use Only

99.98

C15H18ClNS2

311.89

Tipepidine hydrochloride reversibly inhibits dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) with an IC50 of 7.0 microM. Tipepidine hydrochloride subsequently activates VTA dopamine neuron[1]. Tipepidine hydrochloride, a non-narcotic antitussive, exerts an antidepressant-like effect[2].

CN1C/C(CCC1)=C(C2=CC=CS2)\C3=CC=CS3.[H]Cl

2°C to 8°C

12352200